| Zephyrhills to Scottsbluff (Nebraska) | 1,529.63 mi (2,461.69 km) |
| Zephyrhills to Scottsboro (Alabama) | 497.62 mi (800.84 km) |
| Zephyrhills to Scottsdale (Arizona) | 1,792.03 mi (2,883.99 km) |
| Zephyrhills to Scranton (Pennsylvania) | 980.93 mi (1,578.66 km) |
| Zephyrhills to Seabrook (Maryland) | 802.48 mi (1,291.46 km) |
| Zephyrhills to Seabrook (Texas) | 781.88 mi (1,258.32 km) |
| Zephyrhills to Seaford (New York) | 989.81 mi (1,592.94 km) |
| Zephyrhills to Seagoville (Texas) | 907.44 mi (1,460.38 km) |
| Zephyrhills to Seal Beach (California) | 2,148.56 mi (3,457.77 km) |
| Zephyrhills to Searcy (Arkansas) | 740.39 mi (1,191.55 km) |
| Zephyrhills to Seaside (California) | 2,365.36 mi (3,806.67 km) |
| Zephyrhills to SeaTac (Washington) | 2,519.82 mi (4,055.27 km) |
| Zephyrhills to Seattle (Washington) | 2,524.61 mi (4,062.97 km) |
| Zephyrhills to Sebastian (Florida) | 108.30 mi (174.30 km) |
| Zephyrhills to Sebring (Florida) | 68.97 mi (110.99 km) |
