| Zephyrhills to Southchase (Florida) | 48.96 mi (78.80 km) |
| Zephyrhills to Southern Pines (North Carolina) | 507.20 mi (816.27 km) |
| Zephyrhills to Southfield (Michigan) | 985.44 mi (1,585.92 km) |
| Zephyrhills to Southgate (Michigan) | 966.52 mi (1,555.46 km) |
| Zephyrhills to Southlake (Texas) | 946.94 mi (1,523.95 km) |
| Zephyrhills to Spanaway (Washington) | 2,518.43 mi (4,053.03 km) |
| Zephyrhills to Spanish Fork (Utah) | 1,861.25 mi (2,995.38 km) |
| Zephyrhills to Spanish Lake (Missouri) | 862.24 mi (1,387.64 km) |
| Zephyrhills to Spanish Springs (Nevada) | 2,269.41 mi (3,652.27 km) |
| Zephyrhills to Sparks (Nevada) | 2,271.01 mi (3,654.84 km) |
| Zephyrhills to Spartanburg (South Carolina) | 463.39 mi (745.76 km) |
| Zephyrhills to Spearfish (South Dakota) | 1,636.42 mi (2,633.56 km) |
| Zephyrhills to Speedway (Indiana) | 831.26 mi (1,337.79 km) |
| Zephyrhills to Spencer (Iowa) | 1,257.88 mi (2,024.36 km) |
| Zephyrhills to Spokane (Washington) | 2,311.88 mi (3,720.61 km) |
