| Miami (Florida) to Opelousas | 793.31 mi (1,276.71 km) |
| Chicago (Illinois) to Opelousas | 818.82 mi (1,317.76 km) |
| Detroit (Michigan) to Opelousas | 958.00 mi (1,541.76 km) |
| Denver (Colorado) to Opelousas | 962.43 mi (1,548.88 km) |
| Minneapolis (Minnesota) to Opelousas | 999.66 mi (1,608.80 km) |
| Washington (District of Columbia) to Opelousas | 1,030.89 mi (1,659.06 km) |
| Baltimore (Maryland) to Opelousas | 1,063.34 mi (1,711.28 km) |
| Philadelphia (Pennsylvania) to Opelousas | 1,155.80 mi (1,860.08 km) |
| Phoenix (Arizona) to Opelousas | 1,188.51 mi (1,912.73 km) |
| Brooklyn (New York) to Opelousas | 1,231.89 mi (1,982.53 km) |
| New York (New York) to Opelousas | 1,234.50 mi (1,986.73 km) |
| Queens (New York) to Opelousas | 1,242.18 mi (1,999.10 km) |
| Las Vegas (Nevada) to Opelousas | 1,390.64 mi (2,238.02 km) |
| Boston (Massachusetts) to Opelousas | 1,417.23 mi (2,280.81 km) |
| San Diego (California) to Opelousas | 1,477.49 mi (2,377.80 km) |
| Riverside (California) to Opelousas | 1,494.23 mi (2,404.74 km) |
| Los Angeles (California) to Opelousas | 1,552.56 mi (2,498.61 km) |
| San Francisco (California) to Opelousas | 1,797.88 mi (2,893.41 km) |
| Portland (Oregon) to Opelousas | 1,942.44 mi (3,126.06 km) |
| Seattle (Washington) to Opelousas | 1,985.90 mi (3,195.99 km) |
| Houston (Texas) to Opelousas | 204.05 mi (328.38 km) |
| Dallas (Texas) to Opelousas | 316.94 mi (510.06 km) |
| Atlanta (Georgia) to Opelousas | 500.64 mi (805.69 km) |
| St. Louis (Missouri) to Opelousas | 570.01 mi (917.34 km) |
| Tampa (Florida) to Opelousas | 606.39 mi (975.89 km) |
