| Head southwest on Harman Street | 90 m |
| Turn right onto Bushwick Avenue | 2.5 km |
| Turn left onto Grand Street | 900 m |
| Continue onto Borinquen Place | 700 m |
| Take the ramp towards Williamsburg Bridge | 250 m |
| Merge left onto Williamsburg Bridge | 250 m |
| Keep left onto Williamsburg Bridge | 2 km |
| Continue onto Delancey Street | 800 m |
| Continue onto Kenmare Street | 350 m |
| Turn left onto Lafayette Street | 70 m |
| Turn right onto Broome Street | 450 m |
| Continue onto Watts Street | 250 m |
| Take the ramp towards I 78: Holland Tunnel | 100 m |
| Merge left onto Holland Tunnel (I 78) | 3 km |
| Continue onto 14th Street (I 78) | 700 m |
| Keep left towards NJ 139 West: Pulaski Skyway | 500 m |
| Continue onto NJ 139 Lower Level (NJ 139) | 1 km |
| Continue onto Pulaski Skyway (NJ 139) | 150 m |
| Take the ramp towards US 1-9 Truck: Newark | 800 m |
| Merge left onto US 1-9 Truck (US 1 Truck) | 600 m |
| Keep left onto NJ 7 | 2 km |
| Continue straight to stay on Newark-Jersey City Turnpike (CR 508) | 2 km |
| Take the ramp towards I 280 West | 1.5 km |
| Merge right onto Essex Freeway (I 280) | 25 km |
| Keep left towards I 280 West | 700 m |
| Merge right onto Christopher Columbus Highway (I 80) | 35 km |
| Keep left onto Christopher Columbus Highway (I 80) | 40 km |
| Keep straight at the fork | 300 m |
| Merge right onto I 80 | 150 m |
| Keep left onto I 80 | 8 km |
| Keep left onto I 80 | 500 km |
| Keep right onto I 80 | 7 km |
| Take the ramp towards I 80 West | 800 m |
| Keep right towards I 80 West: Cleveland | 700 m |
| Merge left onto Ohio Turnpike (I 80) | 350 km |
| Continue onto Indiana Toll Road (I 80) | 200 km |
| Take exit 21 towards I 80 West: Des Moines | 1 km |
| Keep right towards I 94 West | 150 m |
| Keep left towards I 94 West | 25 km |
| Take exit 1 towards US 41 North: Calumet Avenue | 300 m |
| Keep left towards Calumet Avenue South | 350 m |
| Keep left at the fork | 550 m |
| Merge left onto Borman Expressway (I 80) | 800 m |
| Continue onto Kingery Expressway (I 80) | 1.5 km |
| Take exit 160 towards IL 394 South: Danville | 2.5 km |
| Keep left towards I 80 West | 500 m |
| Merge left onto Tri-State Tollway (I 80) | 8 km |
| Keep right towards I 80 West: Iowa | 50 km |
| Take exit 126A towards I 55 South: Saint Louis | 600 m |
| Merge left onto I 55 | 150 km |
| Keep right towards I 55 South: Saint Louis | 100 km |
| Keep right towards I 72 West: Jacksonville | 150 km |
| Keep right onto I 72 | 10 km |
| Take the ramp towards US 61: New London | 200 m |
| Keep left towards US 61 South: New London | 80 m |
| Make a slight left onto McMasters Avenue (US 61) | 200 m |
| Continue onto Avenue of the Saints (US 61) | 1 km |
| Continue onto McMasters Avenue (US 61) | 2.5 km |
| Continue onto Avenue of the Saints (US 61) | 15 km |
| Take the ramp | 300 m |
| Turn right onto MO 19 | 45 km |
| Enter the traffic circle and take the 2nd exit onto US 54 | 40 m |
| Exit the traffic circle onto US 54 | 15 km |
| Enter the traffic circle and take the 1st exit onto US 54 | 20 m |
| Exit the traffic circle onto US 54 | 15 km |
| Turn left towards US 54 West: Jefferson City | 30 km |
| Take the ramp towards I 70 West: Columbia | 400 m |
| Merge left onto Dwight D. Eisenhower Highway (I 70) | 30 km |
| Continue onto Sheriff Roger I. Wilson Memorial Highway (I 70) | 3 km |
| Continue onto Highway Patrol Sgt. Benjamin Booth Memorial Highway (I 70) | 2.5 km |
| Continue onto Dwight D. Eisenhower Highway (I 70) | 3 km |
| Continue onto U.S. Submarine Veterans' Memorial Highway (I 70) | 90 km |
| Continue onto Dwight D. Eisenhower Highway (I 70) | 80 km |
| Take exit 20 towards MO 7: Blue Springs | 350 m |
| Turn left onto MO 7 | 2 km |
| Turn left | 40 m |
| You have arrived at your destination, on the left | 0 m |
